Scientific Facts on the Biological Effects of Fluorides

Dr David Kennedy DDS
IAOMT
"Fluoridation is the greatest case of scientific fraud of this century"
Robert Carlton, Ph.D., former U.S. EPA scientist on "Marketplace" Canadian Broadcast
Company Nov 24, 1992
"Regarding fluoridation, the EPA should act immediately to protect the
public, not just on the cancer data, but on the evidence of bone fractures,
arthritis, mutagenicity and other effects"
William Marcus, Ph.D., senior EPA toxicologist, Covert Action, Fall 1992, p.66
1.Fluoride exposure disrupts the synthesis of collagen and leads to the breakdown of
collagen in bone, tendon, muscle, skin, cartilage, lungs, kidney and trachea.
A.K. Susheela and Mohan Jha, "Effects of Fluoride on Cortical and Cancellous Bone
Composition", IRCS Medical Sciences: Library Compendium, Vol 9, No.11, pp.1021-
1022
(1981);
Y.D. Sharma, "Effect of Sodium Fluoride on Collagen Cross-Link Precursors",
Toxocological Letters, Vol.10, pp97-100 (1982);
A.K. Susheela and D. Mukerjee, "Fluoride poisoning and the Effect of Collagen
Biosynthesis of Osseous and Nonosseous Tissue", Toxicological European Research,
Vol 3, No.2, pp. 99-104 (1981);
Y.D. Sharma,"Variations in the Metabolism and Maturation of Collagen after Fluoride
Ingestion", Biochemica et Bioiphysica Acta, Vol 715, pp.137-141 (1982);
Marian Drozdz et al.,"Studies on the Influence of Fluoride Compounds upon Connective
Tissue metabolism inGrowing Rats" and "Effect of Sodium Fluoride With and Without
Simultaneous Exposure to Hydrogen Fluoride on Collagen Metabolism", Journal of
Toxological Medicine, Vol. 4, pp.151-157 (1984).
2. Fluoride stimulates granule formation and oxygen consumption in white blood
cells, but inhibits these processes when the white blood cell is challenged by a
foreign agent in the blood.
Robert A. Clark, "Neutrophil Iodintion Reaction Induced by Fluoride: Implications for
Degranulation and Metabolic Activation," Blood, Vol 57, pp.913-921 (1981).
3. Fluoride depletes the energy reserves and the ability of white blood cells to
properly destroy foreign agents by the process of phagocytosis. As little as 0.2 ppm
fluoride stimulates superoxide production in resting white blood cells, virtually
abolishing phagocytosis. Even micro-molar amounts of fluoride, below 1ppm, may
seriously depress the ability of white blood cells to destroy pathogenic agents.
John Curnette, et al, "Fluoride-mediated Activation of the Respiratory Burst in Human
Neutrophils", Journal of Clinical Investigation, Vol 63, pp.637-647 (1979);
W.L. Gabler and P.A. Leong, "Fluoride Inhibition of Polymorphonumclear Leukocytes",
Journal of Dental Research, Vo. 48, No. 9, pp.1933-1939 (1979);
W.L. Gabler, et al., "Effect of Fluoride on the Kinetics of Superoxide Generation by
Fluoride", Journal of Dental Research, Vol. 64, p.281 (1985);A.S. Kozlyuk, et al., "Immune Status of Children in Chemically Contaminated
Environments", Zdravookhranenie, Issue 3, pp.6-9 (1987)
4. Fluoride confuses the immune system and causes it to attack the body's own
tissues, and increases the tumor growth rate in cancer prone individuals.
Alfred Taylor and Nell C. Taylor, "Effect of Sodium Fluoride on Tumor Growth",
Proceedings of the Society for Experimental Biology and Medicine, Vol
119,p.252(1965)
Shiela Gibson, "Effects of Fluoride on Immune System Function", Complementary
Medical Research, Vol 6, pp.111-113 (1992);
Peter Wilkinson, "Inhibition of the Immune Syetem With Low Levels of Fluorides",
Testimony before the Scottish High Court in Edinburgh in the Case of McColl vs.
Strathclyde Regional Council, pp. 17723-18150, 19328-19492, and Exhibit 636,
(1982);
D.W.Allman and M.Benac, "Effect of Inorganic Fluoride Salts on Urine and Cyclic AMP
Concentration in Vivo", Journal of Dental Research, Vol 55 (Supplement B), p.523
(1976);
S. Jaouni and D.W. Allman, "Effect of Sodium Fluoride and Aluminum on Adenylate
Cyclase and Phosphodiesterase Activity", Journal of Dental Research, Vol.64, p.201
(1985)
5. Fluoride inhibits antibody formation in the blood.
S.K. Jain and A.K. Susheela, "Effect of Sodium Fluoride on Antibody Formation in
Rabbits", Environmental Research, Vol.44, pp.117-125 (1987).
6. Fluoride depresses Thyroid activity.
Viktor Gorlitzer Von Mundy, "Influence of Fluorine and Iodine on the Metabolism,
Particularly on the Thyroid Gland," Muenchener Medicische Wochenschrift, Vol 105,
pp182-186 (1963);
Benagiano, "The Effect of Sodium Fluoride on Thyroid Enzymes and Basal Metabolism
in the Rat", Annali Di Stomatologia, Vol 14, pp.601-619n (1965);
Donald Hillman, et al., "Hypothyroidism and Anemia Related to Fluoride in Dairy
Cattle," Journal of Dairy Science, Vol 62, No.3, pp.416-423 (1979);
V. Stole and J. Podoba, "Effect of Fluoride on the Biogenesis of Thrroid Hormones",
Nature, Vol 188, No.4753, pp.855-856 (1960);
Pierre Galleti and Gustave Joyet, "Effect of Fluorine on Thyroid Iodine Metabolism and
yperthyroidism", Journal of Clinical Endocrinology and Metabolism, Vol. 18, pp.1102-
1110 (1958).
7. Fluorides have a disruptive effect on various tissues in the body.
T.Takamorim "The Heart Changes in Growing Albino Rats Fed on Varied Contents oif
Fluorine," The Toxicology of Fluorine, Symposium, Bern, Switzerland, Oct 1962,
pp.125-129; Vilber A.O. Bello and Hillel J. Gitelman, "High Fluoride Exposure in
Hemodialysis Patients", American Journal of Kidney Diseases, Vol. 15, pp.320-324
(1990);
Y.Yoshisa, "Experimental Studies on Chronic Fluorine Poisoning", Japaneses Journal of
Industrial Health, Vol 1, pp.683-690 (1959).8. Flouride promotes development of bone cancer.
J.K. Mauer, et al., "Two-year cacinogenicity study of sodium fluoride in rats", Journal
of the National Cancer Institute, Vol 82, pp1118-1126 (1990);
Proctor and Gamble "Carcinogencity studies with Sodium Fluoride in rats" National
Institute of Environmental Health Sciences Presentation, July 27, 1985;
S.E. Hrudley et al.,"Drinking Water Fluoridation and Osteocarcoma" Canadian Journal
of Public Health, Vol 81, pp.415-416 (1990);
P.D. Cohn, " A Brief Report on the Association of Drinking Water Fluoridation and
Incidence of Osteosarcoma in Young Males", New Jersey Department of Health,
Trenton, New Jersey, Nov 1992; M.C. Mahoney et al.,"Bone Cancer Incidence Rates in
New York", American Journal of Public Health, Vol 81, pp.81, 475 (1991);
Irwin Herskowitz and Isabel Norton, "Increased Incidence of Melanotic Tumors
Following Treatment with Sodium Fluoride", Genetics Vol 48, pp.307-310 (1963);
J.A. Disney, et al., " A Case Study in Testing the Conventional Wisdom; School-Based
Fluoride Mouthrinse Programs in the USA" Community Dentistry and Oral
Epidemiology, Vol 18, pp.46-56 (1990);
D.J. Newell, "Fluoridation of Water Supplies and Cancer – an association?", Applied
Statistics, Vol 26, No.2, pp.125-135 (1977)
9. Fluorides cause premature aging of the human body.
Nicholas Leone, et al., "Medical Aspects of Excessive Fluoride in a Water Supply",
Public Health Reports, Vol 69, pp.925-936 (1954);
J. David Erikson, "Mortality of Selected Cities with Fluoridated and Non-Fluoridated
Water Supplies", New England Journal of Medicine, Vol. 298, pp.1112-1116 (1978);
"The Village Where People are Old
Before their Time", Stern Magazine, Vol 30, pp.107-108,111-112 (1978);
10. Fluoride ingestion from mouthrinses and dentifrices in children is extremely
hazardous to biological development, life span and general health.
Yngve Ericsson and Britta Forsman, "Fluoride retained from mouthrinses and
dentifrices in preschool children", Caries Research, Vol.3, pp.290-299 (1969);
W.L. Augenstein, et al., "Fluoride ingestion in children: a review of 87 cases",
Pediatrics, Vol 88, pp.907-912, (1991);
Charles Wax, "Field Investigation report", State of Maryland Department of Health and
Mental Hygiene, March 19, 1980, 67pp;
George Waldbott, "Mass Intoxication from Over-Fluoridation in Drinking Water",
Clinical Toxicology, Vol 18, No.5, pp.531-541 (1981)
11. Fluorides diminish the intelligence capability of the human brain.
X.S.Li et al, Fluoride, Vol 26, No.4, pp.189-192, 1995, "Effect of Fluoride Exposure on
Intelligence In Children". Presented to the 20th Conference of the International
Society for Fluoride Research, Beijing, China, September 5-9, 1994.
12. Fluoride studies in rats can be indicative of a potential for motor disruption,
intelligence deficits and learning disabilities in humans. Humans are exposed to
plasma levels of fluoride as high as those in rat studies. Fluoride involves interruption
of normal brain development. Fluoride affects the hippocampus in the brain, which
integrates inputs from the environment, memory, and motivational stimuli, to
produce behavioral decisions and modify memory. Experience with otherdevelopmental neurotoxicants prompts expectations that changes in behavioral
functions will be comparable across species, especially humans and rats.
Neurotoxicology and Teratology, Vol 17, No,2, p.176, "Neurotoxicity of Sodium
Fluoride in Rats", Muellenix, Denbesten, Schunior, Kernan, 1995.
13. Fluorides accumulate in the brain over time to reach neurologically harmful
levels.
Neurotoxicology and Teratology, Vol 17, No,2, p.176, "Neurotoxicity of Sodium
Fluoride in Rats", Muellenix, Denbesten, Schunior, Kernan, 1995.
14. "Fluorides are general protoplasma poisons, with the capacity to modify the
metabolism of cells by inhibting certain enzymes. Sources of fluoride intoxication
include drinking water containing 1ppm or more of fluorine."
Journal of the American Medical Association, September 18, 1943.
15. "Drinking water containing as little as 1.2 ppm fluoride will cause developmental
disturbances. We cannot run the risk of producing such serious systemic
disturbances. The potentialities for harm outweigh those for good."
Journal of the American Dental Association, Editorial, October 1, 1944.
Other Facts about Fluoride
The contents of a family-size tube of fluoridated toothpaste is enough to kill a 25-
pound child.
In 1991, the Akron (Ohio) Regional Poison Centre reported that "death has been
reported following ingestion of 16mg/kg of fluoride. Only 1/10 of an ounce of fluoride
could kill a 100 pound adult. According to the Centre, "fluoride toothpaste contains
up to 1mg/gram of fluoride." Even Proctor and Gamble, the makers of Crest,
acknowledge that a family-sized tube "theoretically contains enough fluoride to kill a
small child."
Fluorides have been used to modify behaviour and mood of human beings.
It is a little known fact that fluoride compounds were added to the drinking water of
prisoners to keep them docile and inhibit questioning of authority, both in Nazi prison
camps in World War II and in the Soviet gulags in Siberia.
Fluorides are medically categorized as protoplasmic poisons, which is why they are
used to kill rodents.
1943 The Journal of the American Medical Association on September 18, 1943,
states, "fluorides are general protoplasmic poisons, changing the permeability of the
cell membrane by inhibiting certain enzymes. The exact mechanismof such actions
are obscure.".
Fluoride consumption by human beings increases the general cancer death rate.
1975 Dr. John Yiamouyiannis published a preliminary survey which shows that
people in fluoridated areas have a higher cancer death rate than those in nonfluoridated areas. The National Cancer Institute attempts to refute the studies. Later
in 1975, Yiamouyiannis joins with Dr. Dean Burk, chief chemist of the National
Cancer Institute (1939-1974) in performing other studies which are then included in
the Congressional Record by Congressman Delaney, who was the original author of the Delaney Amendment, which prohibited the addition of cancer-causing substances
to food used for human consumption.
Both reports confirmed the existence of a link between fluoridation and cancer.
(Note: Obviously Dr. Burk felt free to agree with scientific truth only after his tenure
at NCI ended, since his job depended on towing the party line).